Liang Li, Ph.D.
Quantitative Health Sciences /JJN3
Telephone: (216) 445-1929
Fax: (216) 444-8023
Email: lil2 at ccf dot org

Positions: Assistant Staff, Biostatistics, Quantitative Health Sciences, Cleveland Clinic, 2003-present. Education: B.S. Genetics and Cell Biology (1998), Peking University, Beijing, People’s Republic of China. Ph.D. Statistics (2003), University of Wisconsin-Madison. Advisors: Jun Shao (Statistics) and Mari Palta (Population Health Sciences) Key Interests: Statistical: longitudinal and survival analysis, measurement error models, genetic epidemiology. Collaborative: cardiothoracic surgery, chronic renal disease, Parkinson's disease, genetic analysis of arterial thrombosis.

Publications (statistical methodology)

Liang Li, Mari Palta, Jun Shao. (2004). A measurement error model with a Poisson distributed covariate. Statistics in Medicine, 23:2527-2536.

Liang Li, William Wang, Ivan S.F. Chan. (2005) Correlation coefficient inference on censored bioassay data. Journal of Biopharmaceutical Statistics, Vol 15 (3), 501-512.

Liang Li, Jun Shao, Mari Palta. (2005). Longitudinal measurement error model with a semi-continuous regressor. Biometrics, Vol 61, 824-830.

Liang Li, Tom Greene. (2007). Varying coefficients model with measurement error. In press, Biometrics.

Joint modeling of longitudinal and survival data with varying coefficients (with Tom greene, Bo Hu, 2007). Submitted.

Iterative simulation extrapolation with application to complicated survey data. (with Joe Coresh, Tom Greene, 2007). To be submitted.

Best linear unbiased prediction with measurement error correction (with Tom Greene, 2007). To be submitted.

Estimation and model selection in proportional hazard model with time-varying hazard ratios (with Hemant Ishwaran, 2007). Work in progress.

Publications (health sciences applications)

Peer-reviwed Papers

Tamer Said, Ashok Agarwal, Tommaso Falcone, Rakesh K. Sharma, Mohamed A. Bedaiwy, Liang Li (2005). Infliximab may reverse the toxic effects induced by tumor necrosis factor alpha in human spermatozoa: an in vitro model. Fertility and Sterility, 83(6):1665-73.

Tamer Said, Sonja Grunewald, Uwe Paasch, Hans-Juergen Glander, Thomas Baumann, Christian Kriegel, Liang Li, Ashok Agarwal (2005): Advantage of combining magnetic cell separation with sperm preparation techniques. Reproductive Biomedicine Online, 10(6):740-6

Vitaly Siomin, Lilyana Angelov, Liang Li, Michael A. Vogelbaum (2005). Results of a survey of neurosurgical practice patterns regarding the prophylactic use of anti-epilepsy drugs in patients with brain. Journal of Neurooncology, 74(2):211-215.

Rachid Baz, Greg Pearce, Liang Li, Bridget McGowan, Catherine Brand, Erin Yiannaki, Mary Ann Karam, Janice Reed, Beth Faiman, Shannon Brulinski, Rony Abou Jawde, Steven Andresen, Alan Lichtin, Jerome Zeldis, and Mohamad A. Hussein (2005): Aspirin decreases the thrombotic complications of anthracycline based chemotherapy with Thalidomide in the treatment of multiple myeloma. Mayo Clinic Proceedings, 80 (12), 1568-1574.

Colleen G. Koch, Farah Khandwala, Liang Li, Fawzy G. Estafanous, Floyd D. Loop, Eugene H. Blackstone (2006). Persistent effect of perioperative red blood cell transfusion on health-related quality of life following cardiac surgery. Annals of Thoracic Surgery, 82(1), 13-20.

Tamer Said, Ashok Agarwal, Sonja Grunewald, Manja Rasch, Thomas Baumann, Christian Kriegel, Liang Li, Hans-Juergen Glander, Anthony J. Thomas Jr. and Uwe Paasch (2006). Selection of non-apoptotic spermatozoa as a new tool for enhancing assisted reproduction outcomes: an in-vitro model. Biology of Reproduction, 74(3), 530-537.

Colleen G. Koch, Liang Li, Andra I. Duncan, Delos M. Cosgrove, Norman J. Starr, Eugene H. Blackstone (2006). Morbidity and mortality risk associated with red cell and blood component transfusion in isolated coronary artery bypass grafting. Journal of Critical Care Medicine, 34(6), 1608-1616.

Colleen G. Koch, Liang Li, Andra I. Duncan, Tomislav Mihaljevic, Floyd D. Loop, Norman J. Starr, Eugene H. Blackstone (2006). Transfusion in coronary artery bypass grafting is associated with reduced long-term survival. Annals of Thoracic Surgery, 81, 1650-1657.

Michael A. Vogelbaum, Lilyana Angelov, Shih-Yuan Lee, Liang Li, Gene H. Barnett, John H. Suh (2006). Local control of brain metastases by stereotactic radiosurgery depends upon the dose to the tumor margin. Journal of Neurosurgery, 104(6):907-12.

Jacek B. Cywinski, Colleen G. Koch, Liang Li, Norman J. Starr (2006). Risk of postoperative morbidity and mortality with combined coronary artery bypass grafting and carotid endarterectomy: a propensity matched comparison. Journal of Cardiothoracic and Vascular Anesthesia, 20(6):796-802.

Colleen G. Koch, Liang Li, David R. Van Wagoner, Andra I. Duncan, A. Marc Gillinov, Eugene H. Blackstone (2006) Red cell transfusion is associated with increased risk for postoperative atrial fibrillation. Annals of Thoracic Surgery, 82, 1747-1757.

Colleen G. Koch, Liang Li, Andra I. Duncan, Tom Mihaljevic, Delos M. Cosgrove, Floyd D. Loop, Norman J. Starr, Eugene H. Blackstone (2006). Toward an accurate assessment of the adverse effects of packed red blood cell transfusions in cardiac surgery. Journal of Critical Care Medicine Dec;34(12):3068-3069.

Narendra Nathoo, Kene Ugokwe, Albert Chang, Liang Li, Jeffrey Ross, John Suh, Michael A. Vogelbaum, Gene H. Barnett (2006): The role of ¹¹¹ indium-octreotide brain scintigraphy in the diagnosis of cranial, dural-based meningiomas. In press, Journal of Neuro-Oncology.

Colleen G. Koch, Liang Li, Michael Lauer, Joseph Sabik, Norman J. Starr, Eugene H. Blackstone (2007) Effect of functional health-related quality of life on long-term survival following cardiac surgery. Circulation, Feb; 115(6):692-699.

Colleen G. Koch, Liang Li, Daniel I. Sessler, Priscilla Figueroa, Gerald A. Hoeltge, Tomislav Mihaljevic, Eugene H. Blackstone (2007). Red cell storage duration and morbidity and mortality after cardiac surgery. New England Journal of Medicine. In press.

Tory McGrath, Colleen Gorman Koch, Meng Xu, Liang Li, Tomislav Mihaljevec, Priscilla Figueroa, Eugene H. Blackstone. (2007). Platelet transfusion in cardiac surgery does not confer increased risk for adverse morbid outcomes. To be submitted.

Colleen Gorman Koch, Liang Li, Mehdi Shishehbor, Steve Nissen, Joseph Sabik, Norman J. Starr, Eugene H. Blackstone (2007). Socioeconomic status and comorbidity predict preoperative quality of life in cardiac surgery. To be submitted.

Colleen Gorman Koch, Liang Li, Mehdi Shishehbor, Eugene H. Blackstone (2007). Interplay of gender, race, and socioeconomic status with time-related survival after cardiac surgery. To be submitted.

Peer-reviewed Abstracts

Jacek B. Cywinski, Colleen G. Koch, Liang Li, Norman J. Starr (2004). Risk of postoperative morbidity and mortality with combined coronary artery bypass grafting and carotid endarterectomy: a propensity matched comparison (abstract). Society of Cardiovascular Anesthesiologists, Honolulu, Hawaii, 2004. Anesthesia and Analgesia 2004: SCA.

Michael A. Vogelbaum, Lilyana Angelov, Vitaly Siomin, Shih-Yuan Lee, Liang Li (2004). Results of a survey of neurosurgical practice patterns regarding the prophylactic use of anti-epilepsy drugs in patients with brain tumors (abstract). 2004 Congress of Neurological Surgeons Annual Meeting.

Tamer Said, S. Grunewald, U. Paasch, C. Kriegel, Liang Li, HJ Glander, A. Agarwal (2005): Increased sperm oocyte penetration capacity following magnetic cell separation. (oral presentation) In: 30^th Annual Meeting of the American Society of Andrology, April 02-05, Seattle, WA

Tamer Said, U Paasch, S. Grunewald, T. Baumann, Liang Li, HJ Glander, A Agarwal (2005): Advantage of combining magnetic cell separation with sperm preparation techniques. (poster) In: 30^th Annual Meeting of the American Society of Andrology, April 02-05, Seattle, WA

Tamer Said, U Paasch, S. Grunewald, M Rasch, Liang Li, HJ Glander, A Agarwal (2005): Enhancement of sperm cryosurvival rates by magnetic cell sorting. In: 100^th Annual Meeting of the American Urological Association, May 21-26, San Antonio, TX, Abstract # 2978, (Discussed poster)

John S. Seif, Sherif S. Zaky, Liang Li, Marv Leventhal, Allen C. Bashour (2005). A propensity matched comparison of cardiac and non-cardiac thoracic surgery patients on the incidence of new onset postoperative atrial arrhythmias. American Society of Anesthesiologists 2005 Annual Meeting, October 22-26, New Orleans LA

Hesham A. Elsharkawy, Liang Li, Wael Ali Sakr Esa, John Seif, C. Allen Bashour (2007). Arteriovenous extracorporeal membrane oxygenation support associated mortality after cardiac surgery. American Society of Anesthesiologists 2007 Annual Meeting, October 13-17, San Francisco, CA

Lesley A. Stevens, Tom Greene, Liang Li, Christopher H. Schmid, Yaping (Lucy) Zhang, Josef Coresh, Gerald Beck, John Kusek, Andrew S. Levey for the CKD-EPI Collaboration (2007). Factors other than GFR influencing serum cystatin. American Society of Nephrology Meeting, Oct 30-Nov 5, San Francisco, CA

Manuscripts

Hilel Lewis, Liang Li, Julie Thornton (2004). Subretinal fibrinolysis with t-PA and displacement of submacular hemorrhage in age-related macular degeneration.

Farah Khandwala, Colleen G. Koch, Hemant Ishwaran, Liang Li, Eugene H. Blackstone (2005). Emerging trends in the analysis of quality of life data.

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