Lisa received her M.S. in Statistics from Miami University in 1987. She has been in the Department of Biostatistics since January 1990. She is currently a Lead Biostatistician in the Taussig Cancer Center's section of Biostatistics, where she collaborates with physicians and researchers on a wide variety of cancer projects. She also serves as a member of the Cancer Trials Scientific Review Committee, and is a reviewer for the journal of Pediatric Blood and Cancer (formerly the journal of Medical and Pediatric Oncology). In January 2004 she was appointed to the Case Comprehensive Cancer Center's Clinical Trials Development and Review Committee for a 3-year term. Lisa is a member of the American Statistical Association and the American Society of Clinical Oncology. She is actively involved in the Cleveland Chapter of the ASA, and has been a member of the Chapter's Executive Board since 1992.
Donnelly S, Walsh D and Rybicki L. The symptoms of advanced cancer: identification of clinical and research priorities by assessment of prevalence and severity. Journal of Palliative Care, 11(1):27-32, 1995.
Rice TW, Zuccaro G, Adelstein DJ, Rybicki LA, Blackstone EH and Goldblum JR. Esophageal carcinoma: depth of tumor invasion is predictive of regional lymph node status. Annals of Thoracic Surgery, 65(3):787-792, 1998.
Grabowski DR, Dubyak GR, Rybicki L, Hidaka H and Ganapathi R. Tumor cell resistance to topoisomerase II poisons: Role for intracellular free calcium in the sensitization by inhibitors of calcium-calmodulin-dependent enzymes. Biochemical Pharmacology, 56(3):345-349, 1998.
Aoyama M, Grabowski DR, Isaacs RJ, Krivacic KA, Rybicki LA, Bukowski RM, Ganapathi MK, Hickson ID and Ganapathi R. Altered expression and activity of topoisomerases during all-trans retinoic acid-induced differentiation of HL-60 cells. Blood, 92(8):2863-2870, 1998.
Lopez-Kostner F, Lavery IC, Hool GR, Rybicki LA and Fazio VW. Total mesorectal excision is not necessary for cancers of the upper rectum. Surgery, 124(4):612-617, 1998.
Kennedy AW, Markman M, Webster KD, Kulp B, Peterson G, Rybicki LA and Belinson JL. Experience with platinum-paclitaxel chemotherapy in the initial management of papillary serous carcinoma of the peritoneum. Gynecologic Oncology, 71(2):288-290, 1998.
Rice TW, Adelstein DJ, Ciezki JP, Becker ME, Rybicki LA, Farver CF, Larto MA and Blackstone EH. Short-course induction chemoradiotherapy with paclitaxel for stage III non-small-cell lung cancer. Annals of Thoracic Surgery, 66(6):1909-1914, 1998.
Aoyama M, Grabowski DR, Dubyak GR, Constantinous AI, Rybicki LA, Bukowski RM, Ganapathi MK, Hickson ID and Ganapathi R. Attenuation of drug-stimulated topoisomerase II-DNA cleavable complex formation in wild-type HL-60 cells treated with an intracellular calcium buffer is correlated with decreased cytotoxicity and site-specific hypophosphorylation of topoisomerase IIa. Biochemical Journal, 336:727-733, 1998.
Robinson BJ, Rice TW, Strong SA, Rybicki LA and Blackstone EH. Is resection of pulmonary and hepatic metastases warranted in patients with colorectal cancer? Journal of Thoracic and Cardiovascular Surgery, 117(1):66-75, 1999.
Ratanawichitrasin A, Rybicki LA, Steiger E, Grundfest-Broniatowski S, Hermann RE and Crowe JP. Predicting the likelihood of residual disease in women treated for ductal carcinoma in situ. Journal of the American College of Surgeons, 188(1):17-21, 1999.
Yang B, Rice TW, Adelstein DJ, Rybicki LA and Goldblum JR. Overexpression of p53 protein is associated with decreased response to chemoradiotherapy in patients with esophageal carcinoma. Modern Pathology, 12(3):251-256, 1999.
Uzzo RG, Clark PE, Rayman P, Bloom T, Rybicki L, Novick AC, Bukowski RM and Finke JH. Alterations in NFkB activation in T lymphocytes of patients with renal cell carcinoma. Journal of the National Cancer Institute, 91(8):718-721, 1999.
Häfeli UO, Casillas S, Dietz DW, Pauer GJ, Rybicki LA, Conzone SD and Day DE. Hepatic tumor radioembolization in a rat model using radioactive rhenium (186RE/188RE) glass microspheres. International Journal of Radiation Oncology, 44(1):189-199, 1999.
Kolenko V, Rayman P, Roy B, Cathcart MK, O'Shea J, Tubbs R, Rybicki L, Bukowski R and Finke J. Downregulation of JAK3 protein levels in T lymphocytes by prostaglandin E2 and other cyclic adenosine monophosphate-elevating agents: impact on interleukin-2 receptor signaling pathway. Blood, 93(7):2308-2318, 1999.
Nagy JL, Adelstein DJ, Newman CW, Rybicki LA, Rice TW and Lavertu P. Cisplatin ototoxicity: the importance of baseline audiometry. American Journal of Clinical Oncology, 22(3):305-308, 1999.
Adelstein DJ, Rice TW, Rybicki LA, Larto MA, Koka A, Taylor ME, Olencki TE, Peereboom DM and Budd GT. Mature results from a phase II trial of accelerated induction chemoradiotherapy and surgery for poor prognosis stage III non-small cell lung cancer. American Journal of Clinical Oncology, 22(3):237-242, 1999.
Shetty K, Rybicki L, Brzezinski A, Carey WD and Lashner BA. The risk for cancer or dysplasia in ulcerative colitis patients with primary sclerosing cholangitis. American Journal of Gastroenterology, 94(6):1643-1649, 1999.
Banbury MK, Rice TW, Goldblum JR, Clark SB, Baker ME, Richter JE, Rybicki LA and Blackstone EH. Esophagectomy with gastric reconstruction for achalasia. Journal of Thoracic and Cardiovascular Surgery, 117(6):1077-1084, 1999.
Kennedy AW, Markman M, Biscotti CV, Emery JD and Rybicki LA. Survival probability in ovarian clear cell adenocarcinoma. Gynecologic Oncology, 74(1):108-114, 1999.
Schover LR, Rybicki LA, Martin BA and Bringelsen KA. Having children after cancer: a survey of survivors' attitudes and experiences. Cancer, 86(4):697-709, 1999.
Christie NA, Rice TW, DeCamp MM, Goldblum JR, Adelstein DJ, Zuccaro G, Rybicki LA and Blackstone EH. M1b/M1b esophageal carcinoma: clinical relevance. Journal of Thoracic and Cardiovascular Surgery, 118(5):900-907, 1999.
Ciezki JP, Häfeli UO, Song P, Urankar-Nagy N, Ratliff NB, Rybicki L, Brill K and Meier D. Parenchymal cell proliferation in coronary arteries after percutaneous transluminal coronary angioplasty: a human tissue bank study. International Journal of Radiation Oncology, 45(4):963-968,1999.
Grabowski DR, Holmes KA, Aoyama M, Ye Y, Rybicki LA, Bukowski RM, Ganapathi MK, Hickson ID and Ganapathi R. Altered drug interaction and regulation of topoisomerase IIb: potential mechanisms governing sensitivity of HL-60 cells to amsacrine and etoposide. Molecular Pharmacology, 56(6):1340-1345, 1999.
van Stolk R, Stoner G, Hayton WL, Chan K, DeYoung B, Kresty L, Kemmenoe BH, Elson P, Rybicki L, Church J, Provencher K, McLain D, Hawk E, Fryer B, Kelloff G, Ganapathi R and Budd GT. Phase I trial of exisulind (sulindac sulfone, FGN-1) as a chemopreventive agent in patients with familial adenomatous polyposis. Clinical Cancer Research, 6(1):78-89, 2000.
Noshirwani KC, van Stolk RU, Rybicki LA and Beck GJ. Adenoma size and number are predictive of adenoma recurrence: implications for surveillance colonoscopy. Gastrointestinal Endoscopy, 51(4):433-437, 2000.
Adelstein DJ, Rice TW, Rybicki LA, Larto MA, Ciezki J, Saxton J, DeCamp M, Vargo JJ, Dumot JA and Zuccaro G. Does paclitaxel improve the chemoradiotherapy of locoregionally advanced esophageal cancer? A nonrandomized comparison with fluorouracil-based therapy. Journal of Clinical Oncology, 18(10):2032-2039, 2000.
Walsh D, Donnelly S and Rybicki L. The symptoms of advanced cancer: relationship to age, gender, and performance status in 1000 patients. Supportive Care in Cancer, 8(3):175-179, 2000.
DiPierro FV, Rice TW, DeCamp MM, Rybicki LA and Blackstone EH. Esophagectomy and staged reconstruction. European Journal of Cardiothoracic Surgery, 17(6):702-709, 2000.
Kushner DM, Webster KD, Belinson JL, Rybicki LA, Kennedy AW and Markman M. Safety and efficacy of adjuvant single-agent ifosfamide in uterine sarcoma. Gynecologic Oncology, 78(2):221-227, 2000.
Pelley R, Ganapathi R, Wood L, Rybicki L, McLain D, Budd GT, Peereboom D, Olencki T and Bukowski RM. A phase II pharmacodynamic study of pyrazoloacridine in patients with metastatic colorectal cancer. Cancer Chemotherapy and Pharmacology, 46(3):251-254,2000.
Kostic SV, Rice TW, Baker ME, DeCamp MM, Murthy SC, Rybicki LA, Blackstone EH and Richter JE. Timed barium esophagogram: a simple physiologic assessment for achalasia. Journal of Thoracic and Cardiovascular Surgery, 120(5):935-946, 2000.
Stillman MJ and Rybicki LA. The bedside confusion scale: development of a portable bedside test for confusion and its application to the palliative medicine population. Journal of Palliative Medicine, 3(4):449-456, 2000.
Aoyama M, Grabowski DR, Holmes KA, Rybicki LA, Bukowski RM, Ganapathi MK and Ganapathi R. Cell cycle phase specificity in the potentiation of etoposide-induced DNA damage and apoptosis by KN-62, an inhibitor of calcium-calmodulim-dependent enzymes. Biochemical Pharmacology, 61(1):49-54, 2001.
Lopez-Kostner F, Fazio VW, Vignali A, Rybicki LA and Lavery IC. Locally recurrent rectal cancer: predictors and success of salvage surgery. Diseases of the Colon and Rectum, 44(2):173-178, 2001.
Clark PE, Schover LR, Uzzo RG, Hafez KS, Rybicki LA and Novick AC. Quality of life and psychological adaptation after surgical treatment for localized renal cell carcinoma: impact of the amount of remaining renal tissue. Urology, 57(2):252-256, 2001.
Rice TW, Blackstone EH, Adelstein DJ, Zuccaro G, Vargo JJ, Goldblum JR, Rybicki LA, Murthy SC and DeCamp MM. N1 esophageal carcinoma: the importance of staging and downstaging. Journal of Thoracic and Cardiovascular Surgery, 121(3):454-464, 2001.
Bolwell B, Andresen S, Pohlman B, Sobecks R, Goormastic M, Rybicki L, Bell K and Kalaycio M. Prognostic importance of the axillary lymph node ratio in autologous transplantation for high-risk stage II/III breast cancer. Bone Marrow Transplantation, 27:843-846, 2001.
Mekhail TM, Adelstein DJ, Rybicki LA, Larto MA, Saxton JP and Lavertu P. Enteral nutrition during the treatment of head and neck cancer: is a percutaneous endoscopic gastrostomy tube preferable to a nasogastric tube? Cancer, 91(9):1785-1790, 2001.
Tate J, Olencki T, Finke J, Kottke-Marchant K, Rybicki LA and Bukowski RM. Phase I trial of simultaneously administered GM-CSF and IL-6 in patients with renal-cell carcinoma: clinical and laboratory effects. Annals of Oncology, 12:655-659, 2001.
Zanotti KM, Rybicki LA, Kennedy AW, Belinson JL, Webster KD, Kulp B, Peterson G and Markman M. Carboplatin skin testing: a skin-testing protocol for predicting hypersensitivity to carboplatin chemotherapy. Journal of Clinical Oncology, 19(12):3126-3129, 2001.
Malchesky PS, Koo AP and Rybicki LA. Apheresis technologies and clinical applications: the 2000 International Apheresis Registry. Therapeutic Apheresis, 5(3):193-206, 2001.
Donnelly S, Rybicki L and Walsh D. Quality of life measurement in the palliative management of advanced cancer. Supportive Care in Cancer, 9(5):361-365, 2001.
Hussein MA, Sandstrom K, Elson P, Finke J, McLain D, Rayman P, Rybicki LA and Bukowski RM. CM-CSF safety and effects in the management of advanced/refractory multiple myeloma patients: a phase I trial. Journal of Cancer Research and Clinical Oncology, 127(10);619-24, 2001.
Homsi J, Walsh D, Nelson KA, Sarhill N, Rybicki L, LeGrand SB and Davis MP. A phase II study of methylphenidate for depression in advanced cancer. American Journal of Hospice & Palliative Care, 18(6):403-407, 2001.
Rice TW, Blackstone EH, Goldblum JR, DeCamp MM, Murthy SC, Falk GW, Ormsby AH, Rybicki LA, Richter JE and Adelstein DJ. Superficial adenocarcinoma of the esophagus. Journal of Thoracic and Cardiovascular Surgery, 122(6):1077-1090, 2001.
Homsi J, Walsh D, Nelson KA, Sarhill N, Rybicki L, Legrand SB and Davis MP. A phase II study of hydrocodone for cough in advanced cancer. American Journal of Hospice & Palliative Care, 19(1):49-56, 2002.
Adelstein DJ, Saxton JP, Lavertu P, Rybicki LA, Esclamado RM, Wood BG, Strome M and Carroll MA. Maximizing local control and organ preservation in stage IV squamous cell head and neck cancer with hyperfractionated radiation and concurrent chemotherapy. Journal of Clinical Oncology, 20(5):1405-1410, 2002.
Davis MP, Walsh D, Nelson KA, Konrad D, LeGrand SB and Rybicki L. The business of palliative medicine -- part 2: the economics of acute inpatient palliative medicine. American Journal of Hospice & Palliative Care, 19(2):89-95, 2002.
Odze RD, Goldblum J, Noffsinger A, Alsaigh N, Rybicki LA and Fogt F. Interobserver variability in the diagnosis of ulcerative colitis-associated dysplasia by telepathology. Modern Pathology, 15(4):379-386, 2002.
Adelstein DJ, Rice TW, Rybicki LA, Greskovich, JF, Ciezki JP, Carroll MA and DeCamp MM. Accelerated hyperfractionated radiation, concurrent paclitaxel/cisplatin chemotherapy and surgery for stage IIII non-small cell lung cancer. Lung Cancer, 36(2):167-174, 2002.
Bolwell B, Kalaycio M, Sobecks R, Andresen S, McBee M, Kuczkowski L, Rybicki L and Pohlman B. Autologous hematopoietic cell transplantation non-Hodgkin's lymphoma: 100 month follow-up. Bone Marrow Transplantation, 29:673-679, 2002.
Ramalingam P, Rybicki L, Smith MD, Abrahams NA, Tubbs RR, Pettay J, Farver CF and Hsi ED. Posttransplant lymphoproliferative disorders in lung transplant patients: the Cleveland Clinic experience. Modern Pathology, 15(6):647-656, 2002.
Moazami N, Rice TW, Rybicki LA, Adelstein DJ, Murthy SC, DeCamp MM, Barnett GH, Chidel MA, Sugh JH and Blackstone EH. Stage III non-small cell lung cancer and metachronous brain metastases. Journal of Thoracic and Cardiovascular Surgery, 124(1):113-122, 2002.
Walsh D, Rybicki L, Nelson KA and Donnelly S. Symptoms and prognosis in advanced cancer. Supportive Care in Cancer, 10(5):385-388, 2002.
Komurcu S, Nelson KA, Walsh D, Ford RB and Rybicki LA. Gastrointestinal symptoms among inpatients with advanced cancer. American Journal of Hospice & Palliative Care, 19(5):351-355, 2002.
Ross JH, Rybicki L and Kay R. Clinical behavior and a contemporary management algorithm for prepubertal testis tumors: a summary of the prepubertal testis tumor registry. Journal of Urology, 168(4 Pt 2):1675-1678; discussion 1678-1679, 2002.
Skacel M, Petras RE, Rybicki LA, Gramlich TL, Richter JE, Falk GW and Goldblum JR. P53 expression in low grade dysplasia in Barrett's esophagus: correlation with interobserver agreement and disease progression. American Journal of Gastroenterology, 97(10):2508-2513, 2002.
Crowe JP,Rim A, Patrick R, Rybicki L, Grundfest S, Kim J, Lee K and Levy L. A prospective review of the decline of excisional breaset biopsy. Am J Surg Oct, 184(4):353-355, 2002.
Ormsby AH, Petras RE, Henricks WH, Rice TW, Rybicki LA, Richter JE and Goldblum JR. Observer variation in the diagnosis of superficial oesophageal adenocarcinoma. Gut, 51(5):671-6, 2002.
Bolwell BJ, Kalaycio M, Sobecks R, Andresen S, Kuczkowski E, Bernhard L, Lomax R, Kohuth J, Mendiola S, Rybicki L and Pohlman B. A multivariable analysis of factors influencing mucositis after autologous progenitor cell transplantation. Bone Marrow Transplantation, 30(9):587-591, 2002.
Abrahams NA, Halverson A, Fazio VW, Rybicki LA and Goldblum JR. Adenocarcinoma of the small bowel: a study of 37 cases with emphasis on histologic prognostic factors. Diseases of the Colon and Rectum, 45(11):1496-1502, 2002.
Castilla EA, Liou LS, Abrahams NA, Fergany A, Rybicki LA, Myles J and Novick AC. Prognostic importance of resection margin width after nephron-sparing surgery for renal cell carcinoma. Urology, 60(6):993-997, 2002.
Bolwell B, Sobecks R, Pohlman B, Andresen S, Theil K, Serafino S, Rybicki L and Kalaycio M. Etoposide (VP-16) plus G-CSF mobilizes different dendritic cell subsets than does G-CSF alone. Bone Marrow Transplantation, 31:95-98, 2003.
Perez-Zincer F, Juturi JV, Hsi ED, Hoeltge GA, Rybicki LA and Kalaycio ME. A pulmonary syndrome in patients with acute myelomonocytic leukemia and inversion of chromosome 16. Leukemia & Lymphoma, 44(1):103-109, 2003.
He X-Y, Pohlman B, Lichtin A, Rybicki L and Kalaycio M. Timed sequential chemotherapy with concomitant granulocyte colony-stimulating factor for newly diagnosed de novo acute myelogenous leukemia. Leukemia, 17(6):1078-1084, 2003.
Rice TW, Blackstone EH, Adelstein DJ, Zuccaro G Jr, Vargo JJ, Goldblum JR, Murthy SC,
DeCamp MM and Rybicki LA. Role of clinically determined depth of tumor invasion in the treatment of esophageal carcinoma. Journal of Thoracic and Cardiovascular Surgery, 125(5):1091-1102, 2003.
Rice TW, Blackstone EH, Rybicki LA, Adelstein DJ, Murthy SC, DeCamp MM and Goldblum JR. Refining esophageal cancer staging. Journal of Thoracic and Cardiovascular Surgery, 125(5):1103-1113, 2003.
Lashner BA, Bauer WM, Rybicki LA and Goldblum JR. Abnormal p53 immunohistochemistry is associated with an increased colorectal cancer-related mortality in patients with ulcerative colitis. American Journal of Gastroenterology, 98(6):1423-1427, 2003.
Agrawal NR, Bukowski RM, Rybicki LA, Kurtzberg J, Cohen LJ, and Hussein MA. A phase I-II trial of polyethylene glycol-conjugated L-asparaginase in patients with multiple myeloma. Cancer, 98(1):94-99, 2003.
DeCamp MM, Rice TW, Adelstein DJ, Chidel MA, Rybicki LA, Murthy SC, and Blackstone EH. Value of accelerated multimodality therapy in stage IIIA and IIIB non-small cell lung cancer. Journal of Thoracic and Cardiovascular Surgery, 126(1):17-27, 2003.
Sarhill N, Mahmoud F, Walsh D, Nelson KA, Komurcu, S, Davis M, LeGrand S, Abdullah O and Rybicki L. Evaluation of nutritional status in advanced metastatic cancer. Supportive Care in Cancer, 11(10):652-659, 2003.
McHam SA, Adelstein DJ, Rybicki LA, Lavertu P, Esclamado RM, Wood BG, Strome M and Carroll MA. Who merits a neck dissection after definitive chemoradiotherapy for N2-N3 squamous cell head and neck cancer? Head and Neck, 25(10):791-798, 2003.
Castilla EA, Prayson RA, Kanner AA, Rybicki LA, Tubbs RT, Vogelbaum MA and Barnett GH. Cyclooxygenase-2 in oligodendroglial neoplasms. Cancer, 98(7):1465-1472, 2003.
Hussein MA, Juturi JV, Rybicki L, Lutton S, Murphy BR and Karam MA. Etanercept therapy in patients with advanced primary amyloidosis. Medical Oncology, 20(3):283-290, 2003.
Ramalingam P, Chu WS, Tubbs R, Rybicki L, Pettay J and Hsi ED. Latent membrane protein 1, tumor necrosis factor receptor-associated factor (TRAF) 1, TRAF-2, TRAF-3 and nuclear factor kappa B expression in posttransplant lymphoproliferative disorders. Archives of Pathology and Laboratory Medicine, 127(10):1335-1339, 2003.
Crowe JP, Patrick RJ, Rybicki LA, Grundfest SF, Kim JA, Lee KB and Rim A. Does ultrasound core breast biopsy predict histologic findings on excisional biopsy? American Journal of Surgery, 186(4):397-399, 2003.
Crowe JP, Rim A, Patrick RJ, Rybicki LA, Grundfest-Broniatowski SF, Kim JA and Lee KB. Does core needle breast biopsy accurately reflect breast pathology? Surgery, 134(4):523-526, 2003.
Rice TW, Adelstein DJ, Chidel MA, Rybicki LA, DeCamp MM, Murthy SC, and Blackstone EH. Benefit of postoperative adjuvant chemoradiotherapy in locoregionally advanced esophageal carcinoma. Journal of Thoracic and Cardiovascular Surgery, 126(5):1590-1596, 2003.
Chiesa-Vottero AG, Rybicki LA and Prayson RA. Comparison of proliferation indices in glioblastoma multiforme by whole tissue section versus tissue microarray. American Journal of Clinical Pathology, 120(6):902-906, 2003.
Hussein MA, George R, Rybicki L and Karam MA. Skeletal trauma preceeding the development of plasma cell dyscrasia: eight case reports and review of the literature. Medical Oncology, 20(4):349-354, 2003.
Bolwell B, Pohlman B, Sobecks R, Andresen S, Brown S, Rybicki L, Wentling V, and Kalaycio M. Prognostic importance of the platelet count 100 days post allogeneic bone marrow transplant. Bone Marrow Transplantation, 33(4):419-423, 2004.