Positions: Vice Chair, Quantitative Health Sciences, The Cleveland Clinic Foundation, 2005-present Full Staff, Quantitative Health Sciences, and Division of Radiology, 2005-present Full Staff, Biostatistics and Epidemiology, and Division of Radiology, 2003-2004 Education: PhD, Biometry, University of Pittsburgh, 1991 Honors/Service: Regional Advisory Board, ENAR 1994-96 Chief Editor, Fundamentals of Clinical Research For Radiologists series, ACR-AJR, 2003-present

Key Interests:
Dr. Obuchowski has collaborated with investigators in the Division of Radiology at the Cleveland Clinic for 14 years. She works on the design and analysis of studies of screening and diagnostic tests. Dr. Obuchowski’s methodologic research involves Receiver Operating Characteristic (ROC) curves. She has developed methods for sample size determination of multi-reader ROC studies, estimating and comparing the accuracies of tests from clustered data, extending ROC analysis to situations where the outcome is not binary, but nominal, ordinal, or continuous, and testing the equivalence of diagnostic tests. She wrote a book titled Statistical Methods in Diagnostic Methods by Zhou, Obuchowski, and McClish (2002).

Selected Publications:
Jensen MC, Brant-Zawadzki MN, Obuchowski N, Modic M and Ross JS. MRI of the Lumbar Spine II: The Asymptomatic Subject. New England Journal of Medicine, 1994; 331:69-73.

Obuchowski NA. Multi-reader Multi-modality ROC Studies: Hypothesis Testing and Sample Size Estimation Using an ANOVA Approach with Dependent Observations. Academic Radiology, 1995: 2:522-529.

Obuchowski NA. Nonparametric Analysis of Clustered ROC Curve Data. Biometrics, 1997; 53:170-180.

Obuchowski NA, Modic MT, Magdinec M and Masaryk TJ. An Assessment of the Efficacy of Noninvasive Screening for Patients with Asymptomatic Neck Bruits. Stroke, 1997; 28:1330-1339.

Obuchowski NA. On the Comparison of Correlated Proportions for Clustered Data. Statistics in Medicine, 1998: 17: 1495-1507.

Obuchowski NA. Sample Size Calculations in Studies of Test Accuracy. Statistical Methods in Medical Research 1998; 7: 371-392.

Obuchowski NA, Goske MJ, Applegate KE. Assessing physicians’ accuracy in diagnosing paediatric patients with acute abdominal pain: measuring accuracy for multiple diseases. Statistics in Medicine, 2001: 20: 3261-3278.

Obuchowski NA, Zhou XH. Prospective studies of diagnostic test accuracy when disease prevalence is low. Biostatistics 2002; 3:477-492.